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Article

AQP0-LTR of the Cat Fr mouse alters water permeability and calcium regulation of wild type AQP0.

Biochimica et biophysica acta - 1 Aug 2006

Kalman Katalin, Németh-Cahalan Karin L, Froger Alexandrine, Hall James E

Abstract excerpt

Aquaporin 0 (AQP0) is the major intrinsic protein of the lens and its water permeability can be modulated by changes in pH and Ca2+. The Cataract Fraser (Cat Fr) mouse accumulates an aberrant AQP0 (AQP0-LTR) in sub-cellular compartments resulting in a congenital cataract. We investigated the interference of AQP0-LTR with normal function of AQP0 in three systems. First, we created a transgenic mouse expressing...

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Identifiers

PMID: 16515771
DOI: 10.1016/j.bbamem.2006.01.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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