Article
The role of MIP in lens fiber cell membrane transport.
The Journal of membrane biology - 1 Aug 1999
Varadaraj K, Kushmerick C, Baldo G J, Bassnett S, Shiels A, Mathias R T
Abstract excerpt
MIP has been hypothesized to be a gap junction protein, a membrane ion channel, a membrane water channel and a facilitator of glycerol transport and metabolism. These possible roles have been indirectly suggested by the localization of MIP in lens gap junctional plaques and the properties of MIP when reconstituted into artificial membranes or exogenously expressed in oocytes. We have examined lens fiber cells to...
Topics
- Animals
- Anura
- Aquaporins
- Cell Membrane Permeability
- Electric Conductivity
- Epithelial Cells
- Eye Proteins
- Gap Junctions
- Glycerol
- Ion Channels
- Lens Cortex, Crystalline
- Male
- Membrane Glycoproteins
- Mice
- Mutation
- Rabbits
- Water
