Article
Either bacteriophage T4 RNase H or Escherichia coli DNA polymerase I is essential for phage replication.
Journal of bacteriology - 1 Dec 1996
Hobbs L J, Nossal N G
Abstract excerpt
Bacteriophage T4 rnh encodes an RNase H that removes ribopentamer primers from nascent DNA chains during synthesis by the T4 multienzyme replication system in vitro (H. C. Hollingsworth and N. G. Nossal, J. Biol. Chem. 266:1888-1897, 1991). This paper demonstrates that either T4 RNase HI or Escherichia coli DNA polymerase I (Pol I) is essential for phage replication. Wild-type T4 phage production was not...
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