Article
Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia.
Blood - 15 Jun 2006
Monzo Mariano, Brunet Salut, Urbano-Ispizua Alvaro, Navarro Alfons, Perea Granada, Esteve Jordi, Artells Rosa, Granell Miquel, Berlanga Juan, Ribera Josep M, Bueno Javier, Llorente Andreu, Guardia Ramon, Tormo Mar, Torres Pio, Nomdedéu Josep F, Montserrat Emili, Sierra Jordi
Abstract excerpt
Current prognostic factors for acute myeloblastic leukemia (AML) are not sufficient to accurately predict the group of patients in the intermediate-risk category who will successfully respond to treatment. Distinct patterns of inherited functional genomic polymorphisms might explain part of these heterogeneous prognoses. We used the allelic discrimination method to identify polymorphisms in GSTT1, SULT1C2, CDA,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
