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Article

The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer.

International journal of cancer - 1 Aug 2006

Bilbao Cristina, Rodríguez Germán, Ramírez Raquel, Falcón Orlando, León Laureano, Chirino Ricardo, Rivero Juan F, Falcón Orlando, Díaz-Chico B Nicolás, Díaz-Chico Juan C, Perucho Manuel

Abstract excerpt

Microsatellite instability (MSI) and mutations in the PTEN gene are among the molecular alterations involved in endometrial carcinogenesis. There is conflicting information regarding to their role in this type of tumor. For this reason, we have studied both molecular lesions in a large population-based series of 205 patients with sporadic endometrial cancer. MSI was found in 41 (20.0%) of the tumors and PTEN...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16506206
DOI: 10.1002/ijc.21862

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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