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A study on oncogenic role of leptin and leptin receptor in oral squamous cell.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2015

Hussain Syed Rizwan, Naqvi Hena, Gupta Shalini, Mahdi Abbas Ali, Kumari Pratibha, Waseem Mohammad, Ahmad Mohammad Kaleem

Abstract excerpt

Leptin been mainly produced by adipose tissue and cancer cells is the most studied adipokine, amongst the several cytokines. Leptin is an antiapoptotic molecule and inducer of cancer stem cells as well as activates cell proliferation. Its oncogenic, mitogenic, proinflammatory and proangiogenic actions lead to its vital roles in tumourigenesis. Two common functional DNA polymorphisms in the genes of leptin G2548A...

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Carcinoma, Squamous Cell
Gene Frequency
Genetic Association Studies
India
Leptin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mouth Neoplasms

Receptors, Leptin

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Identifiers

PMID: 25809704
DOI: 10.1007/s13277-015-3342-1

Genes

LEP
LEPR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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