Article
No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults.
Journal of psychiatric research - 1 Aug 2007
Surtees Paul G, Wainwright Nicholas W J, Willis-Owen Saffron A G, Sandhu Manjinder S, Luben Robert, Day Nicholas E, Flint Jonathan
Abstract excerpt
Recent research has suggested that brain-derived neurotrophic factor (BDNF) may be implicated in the aetiology of mood-related phenotypes. Here we report an investigation of the association between a BDNF coding variant (Val66Met, rs6265) and mood status in a large non-clinical sample of men and women. We genotyped 7389 adult men and women, aged 41-80 years, selected from participants in the European Prospective...
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