Article
The significant association of CCND1 genotypes with colorectal cancer in Taiwan.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2015
Huang Chung-Yu, Tsai Chia-Wen, Hsu Chin-Mu, Chang Wen-Shin, Shui Hao-Ai, Bau Da-Tian
Abstract excerpt
Colorectal cancer, one million cases of diagnosis worldwide annually, is one of the most common malignant tumors and 20 % incidence caused by low penetrance susceptibility genes. Cyclin D1 (CCND1) regulating cell cycle transition may determine the susceptible individuals to genomic instability and carcinogenesis. The study aimed at examining the contribution of CCND1 genotypes to colorectal cancer risk in Taiwan....
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