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Article

Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients.

Journal of human genetics - 1 Jan 2011

Bonilla Carolina, Lefèvre Jérémie H, Winney Bruce, Johnstone Elaine, Tonks Susan, Colas Chrystelle, Day Tammy, Hutnik Katarzyna, Boumertit Abdelhamid, Midgley Rachel, Kerr David, Parc Yann, Bodmer Walter F

Abstract excerpt

We examined the influence that rare variants and low-frequency polymorphisms in the cancer candidate gene CCND1 have on the development of multiple intestinal adenomas and the early onset of colorectal cancer. Individuals with <100 multiple polyps and patients with colorectal cancer diagnosed before 50 years of age were recruited in UK, and screened for sequence changes in the coding and regulatory regions of...

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Identifiers

PMID: 21107342
DOI: 10.1038/jhg.2010.144
PMCID: PMC5140020

Genes

CCND1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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