Article
Surveillance of women at high risk for hereditary ovarian cancer is inefficient.
British journal of cancer - 27 Mar 2006
Oei A L, Massuger L F, Bulten J, Ligtenberg M J, Hoogerbrugge N, de Hullu J A
Abstract excerpt
To determine the effectiveness of annual gynaecological screening (pelvic examination, transvaginal ultrasound, and CA-125), a prospective cohort study of women at high risk for hereditary ovarian cancer was conducted. Women were offered DNA analysis followed by either annual screening or prophylactic bilateral salpingo-oophorectomy (BSO). Study population consisted of 512 high-risk women (median follow-up 2.07...
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