Article
Outcome of surveillance and prophylactic salpingo-oophorectomy in asymptomatic women at high risk for ovarian cancer.
Gynecologic oncology - 1 May 2005
Meeuwissen Paul A M, Seynaeve Caroline, Brekelmans Cecile T M, Meijers-Heijboer Hanne J, Klijn Jan G M, Burger Curt W
Abstract excerpt
OBJECTIVE: Women at high risk of ovarian cancer are currently offered two options: either surveillance or prophylactic bilateral salpingo-oophorectomy. The efficacy and outcome of surveillance remain unclear. METHODS: We performed a retrospective study. Between 1994 and 2000, we screened 383 high-risk women, of which 152 were BRCA1/2 mutation carriers. Surveillance consisted of annual gynecological examination,...
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