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Article

High risk for ovarian cancer in a prospective series is restricted to BRCA1/2 mutation carriers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2008

Maehle Lovise, Apold Jaran, Paulsen Torbjørn, Hagen Bjørn, Løvslett Kjell, Fiane Bent, Van Ghelue Marijke, Clark Neal, Møller Pål

Abstract excerpt

PURPOSE: Inherited ovarian cancer carries a serious prognosis. Prophylactic oophorectomy has been advocated. The degree to which inherited ovarian cancer is restricted to BRCA mutation carriers is not fully known. We wanted to determine the prevalence of BRCA mutation carriers in women at high risk from ovarian cancer. EXPERIMENTAL DESIGN: Healthy women who were found to be at increased risk judged by family...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19010876
DOI: 10.1158/1078-0432.CCR-08-0112

Genes

BRCA1

Provenance

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