Article
Hereditary ovarian cancer--assessing risk and prevention strategies.
Obstetrics and gynecology clinics of North America - 1 Dec 2007
Pavelka James C, Li Andrew J, Karlan Beth Y
Abstract excerpt
Hereditary ovarian cancers are almost entirely attributable to mutations in BRCA1/2 or the genes of DNA mismatch repair. Identifying individuals at risk requires a complete family history and evidence-guided genetic testing. Screening of women at increased risk for ovarian cancer can be considered in those not wishing prophylactic surgery and typically should include a twice-annual pelvic examination, serum...
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