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Article

Efficacy of screening women at high risk of hereditary ovarian cancer: results of an 11-year cohort study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000

Gaarenstroom K N, van der Hiel B, Tollenaar R A E M, Vink G R, Jansen F W, van Asperen C J, Kenter G G

Abstract excerpt

The outcome of screening and prophylactic surgery in 269 women at high risk of hereditary ovarian cancer is reported. Screening was performed using transvaginal ultrasound and serum CA125 testing. Mean follow-up was 26 months (583 person-years). A total of 113 (42%) of 269 women had a pathogenic BRCA1 or BRCA2 mutation, and 127 (47%) of 269 women underwent salpingo-oophorectomy. No occult cancers were found. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16515568
DOI: 10.1111/j.1525-1438.2006.00480.x

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Efficacy of screening women at high risk of hereditary ovarian cancer: results of an 11-year cohort study.PMID 16515568Read ↗

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