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Article

Neuronal vulnerability in transgenic mice expressing an inducible dominant-negative FGF receptor.

Experimental neurology - 1 Apr 2006

Eckenstein Felix P, McGovern Toby, Kern Drew, Deignan Jason

Abstract excerpt

Fibroblast Growth Factors (FGFs) and their receptors (FGFRs) are widely expressed in the mature nervous system and are thought to mediate plasticity and repair. We report the generation of transgenic mice that can be induced to express a dominant-negative FGFR (dnFGFR) in select neuronal populations. We show that a modified Thy1 promoter [Vidal, M., Morris, R., Grosveld, F., and Spanopoulou, E. 1990....

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Identifiers

PMID: 16487970
DOI: 10.1016/j.expneurol.2005.12.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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