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Article

An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins.

Molecular biology of the cell - 1 Mar 2006

Gullapalli Anuradha, Wolfe Breann L, Griffin Courtney T, Magnuson Terry, Trejo JoAnn

Abstract excerpt

Sorting nexin 1 (SNX1) and SNX2 are the mammalian homologues of the yeast Vps5p retromer component that functions in endosome-to-Golgi trafficking. SNX1 is also implicated in endosome-to-lysosome sorting of cell surface receptors, although its requirement in this process remains to be determined....

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Share to Endosomal Sorting Complexes Required for Transport
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Processing, Post-Translational

Share to Receptor, PAR-1

Share to RNA, Small Interfering

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Source

Open in PubMed Open full text

Identifiers

PMID: 16407403
DOI: 10.1091/mbc.e05-09-0899
PMCID: PMC1382312

Genes

SNX1
SNX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16407403-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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