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Article

Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2.

Proceedings of the National Academy of Sciences of the United States of America - 18 Oct 2005

Griffin Courtney T, Trejo JoAnn, Magnuson Terry

Abstract excerpt

We have previously shown that the putative mammalian retromer components sorting nexins 1 and 2 (Snx1 and Snx2) result in embryonic lethality when simultaneously targeted for deletion in mice, whereas others have shown that Hbeta58 (also known as mVps26), another retromer component, results in similar lethality when targeted for deletion. In the current study, we address the genetic interaction of these mammalian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 16214895
DOI: 10.1073/pnas.0409558102
PMCID: PMC1257690

Genes

SNX2
SNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2.PMID 16214895Read ↗

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