Article
No association of the Arg51Gln and Leu72Met polymorphisms of the ghrelin gene and polycystic ovary syndrome.
Human reproduction (Oxford, England) - 1 Feb 2009
Wang Kehua, Wang Leiguang, Zhao Yueran, Shi Yuhua, Wang Laicheng, Chen Zi-Jiang
Abstract excerpt
BACKGROUND: Ghrelin plays a role in regulating glucose metabolism and energy balance. Polymorphisms in preproghrelin and ghrelin gene could be responsible for obesity, insulin resistance and low ghrelin levels observed in some individuals. The objective of this study was to evaluate the influence of two single-nucleotide polymorphisms (SNPs) of ghrelin gene on the clinical, the hormonal and metabolic features in...
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