Article
The Leu72Met polymorphism of the ghrelin gene is associated with a decreased risk for type 2 diabetes.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2009
Berthold Heiner K, Giannakidou Eleni, Krone Wilhelm, Mantzoros Christos S, Gouni-Berthold Ioanna
Abstract excerpt
BACKGROUND: Ghrelin is involved in several metabolic and cardiovascular processes. The Leu72Met polymorphism of its gene was associated with an increased risk of type 2 diabetes (DM2) in some, but not all studies. Its association with atherosclerosis is not known. METHODS: We investigated 420 Caucasian subjects with DM2 and 430 controls without diabetes (56.6% male, age 62+/-10 years). RESULTS: The Leu72Leu...
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