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Article

Mutations in the preproghrelin/ghrelin gene associated with obesity in humans.

The Journal of clinical endocrinology and metabolism - 1 Aug 2001

Ukkola O, Ravussin E, Jacobson P, Snyder E E, Chagnon M, Sjöström L, Bouchard C

Abstract excerpt

Ghrelin and preproghrelin sequences were determined in 96 unrelated female subjects with severe obesity (mean body mass index (BMI) 42.3 +/- 3.4 kg/m(2)) and in 96 non-obese female controls (mean BMI 23.0 +/- 1.4 (kg/m2) of the Swedish Obese Subjects cohort. A mutation at amino acid position 51 (Arg51Gln) of the preproghrelin sequence that corresponds to the last amino acid in mature ghrelin product was...

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PMID: 11502844
DOI: 10.1210/jcem.86.8.7914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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