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Article

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans.

Nature - 16 Feb 2006

Aitman Timothy J, Dong Rong, Vyse Timothy J, Norsworthy Penny J, Johnson Michelle D, Smith Jennifer, Mangion Jonathan, Roberton-Lowe Cheri, Marshall Amy J, Petretto Enrico, Hodges Matthew D, Bhangal Gurjeet, Patel Sheetal G, Sheehan-Rooney Kelly, Duda Mark, Cook Paul R, Evans David J, Domin Jan, Flint Jonathan, Boyle Joseph J, Pusey Charles D, Cook H Terence

Abstract excerpt

Identification of the genes underlying complex phenotypes and the definition of the evolutionary forces that have shaped eukaryotic genomes are among the current challenges in molecular genetics. Variation in gene copy number is increasingly recognized as a source of inter-individual differences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16482158
DOI: 10.1038/nature04489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16482158-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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