Article
Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease.
International immunology - 1 Jan 2010
Zhou Xu-jie, Lv Ji-cheng, Bu Ding-fang, Yu Lei, Yang Yan-rong, Zhao Juan, Cui Zhao, Yang Rui, Zhao Ming-Hui, Zhang Hong
Abstract excerpt
Anti-glomerular basement membrane antibody disease (anti-GBM disease) is a rare disorder characteristic of universally poor outcome. Fcgamma receptors (FcgammaRs) play important roles in anti-GBM disease based on evidence from animal models. Copy number variation (CNV) influences disease suscepti...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
