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Article

Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease.

International immunology - 1 Jan 2010

Zhou Xu-jie, Lv Ji-cheng, Bu Ding-fang, Yu Lei, Yang Yan-rong, Zhao Juan, Cui Zhao, Yang Rui, Zhao Ming-Hui, Zhang Hong

Abstract excerpt

Anti-glomerular basement membrane antibody disease (anti-GBM disease) is a rare disorder characteristic of universally poor outcome. Fcgamma receptors (FcgammaRs) play important roles in anti-GBM disease based on evidence from animal models. Copy number variation (CNV) influences disease susceptibility. The FcgammaRs genes show CNV, and CNV of the FCGR3B gene is associated with glomerulonephritis in systemic...

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PMID: 19946017
DOI: 10.1093/intimm/dxp113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease.PMID 19946017Read ↗

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