Article
Copy number variation in autoimmunity--importance hidden in complexity?
European journal of immunology - 1 Aug 2012
Olsson Lina M, Holmdahl Rikard
Abstract excerpt
Copy number variation, namely regions of the genome that can be either deleted or duplicated in a variable way, has emerged as an important source of genetic variance in the human genome. Genes with immunological functions are particularly prone to copy number variation, in part because this is a mechanism to expand the recognition repertoire; however, immunological genes not directly involved in immune...
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