Article
Identification of the segments of the mouse transferrin receptor 1 required for mouse mammary tumor virus infection.
The Journal of biological chemistry - 14 Apr 2006
Wang Enxiu, Albritton Lorraine, Ross Susan R
Abstract excerpt
Most enveloped viruses enter cells through binding of virion surface envelope proteins to receptors found on the plasma membrane of the cell. The beta retrovirus mouse mammary tumor virus (MMTV) uses transferrin receptor 1 (TfR1) to enter cells in a pH-dependent mechanism, probably co-trafficking with TfR1 to an acidic compartment where virus entry occurs. We have shown here that, although mouse and rat TfR1...
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