Article
A major determinant for membrane protein interaction localizes to the carboxy-terminal domain of the mouse coronavirus nucleocapsid protein.
Journal of virology - 1 Nov 2005
Hurst Kelley R, Kuo Lili, Koetzner Cheri A, Ye Rong, Hsue Bilan, Masters Paul S
Abstract excerpt
The two major constituents of coronavirus virions are the membrane (M) and nucleocapsid (N) proteins. The M protein is anchored in the viral envelope by three transmembrane segments flanked by a short amino-terminal ectodomain and a large carboxy-terminal endodomain. The M endodomain interacts with the viral nucleocapsid, which consists of the positive-strand RNA genome helically encapsidated by N protein...
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