Article
Role of MSK1 in the signaling pathway leading to VEGF-mediated PAF synthesis in endothelial cells.
Journal of cellular biochemistry - 1 Aug 2006
Marchand Catherine, Favier Judith, Sirois Martin G
Abstract excerpt
Vascular endothelial growth factor (VEGF) inflammatory effects require acute platelet-activating factor (PAF) synthesis by endothelial cells (EC). We previously reported that VEGF-mediated PAF synthesis involves the activation of VEGF receptor-2/Neuropilin-1 complex, which is leading to the activation of p38 and p42/44 mitogen-activated protein kinases (MAPKs) and group V secretory phospholipase A(2) (sPLA(2)-V)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
