Article

The role and regulation of VEGF-mediated ERK5 activity in endothelial cells

2014-01-01

Abstract excerpt

Extracellular signal-regulated kinase 5 (ERK5) is the newest member of the mitogen- activated protein kinase (MAPK) family following the discovery of ERK1/2, JNK and p38 MAPK. ERK5 consists of an N-terminal kinase domain, similar to the other MAPK members, and a large C-terminal domain, which is unique in structure and function from the other MAPK members. ERK5 is activated in response to a multitude of extracellu...

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Literature Corpus work: 9b6c7ad3-3c44-5855-aeb0-cc35d0f0ef97
DOI: 10.17638/02008164

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