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Article

Drosophila melanogaster gamma-TuRC is dispensable for targeting gamma-tubulin to the centrosome and microtubule nucleation.

The Journal of cell biology - 13 Feb 2006

Vérollet Christel, Colombié Nathalie, Daubon Thomas, Bourbon Henri-Marc, Wright Michel, Raynaud-Messina Brigitte

Abstract excerpt

In metazoans, gamma-tubulin acts within two main complexes, gamma-tubulin small complexes (gamma-TuSCs) and gamma-tubulin ring complexes (gamma-TuRCs). In higher eukaryotes, it is assumed that microtubule nucleation at the centrosome depends on gamma-TuRCs, but the role of gamma-TuRC components remains undefined. For the first time, we analyzed the function of all four gamma-TuRC-specific subunits in Drosophila...

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Identifiers

PMID: 16476773
DOI: 10.1083/jcb.200511071
PMCID: PMC2063672

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Source receipt: pubmed, retrieved 7 Sept 2026.

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