Article
The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline.
Development (Cambridge, England) - 1 Oct 2006
Vogt Nina, Koch Iris, Schwarz Heinz, Schnorrer Frank, Nüsslein-Volhard Christiane
Abstract excerpt
The gamma-tubulin ring complex (gammaTuRC) forms an essential template for microtubule nucleation in animal cells. The molecular composition of the gammaTuRC has been described; however, the functions of the subunits proposed to form the cap structure remain to be characterized in vivo. In Drosophila, the core components of the gammaTuRC are essential for mitosis, whereas the cap component Grip75 is not required...
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