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The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon‐α‐stimulated host cells

11 Oct 2005

Abstract excerpt

Hepatitis delta virus (HDV) RNA editing controls the formation of hepatitis-delta-antigen-S and -L and therefore indirectly regulates HDV replication. Editing is thought to be catalysed by the adenosine deaminase acting on RNA1 (ADAR1) of which two different forms exist, interferon (IFN)-alpha-inducible ADAR1-L and constitutively expressed ADAR1-S. ADAR1-L is hypothesized to be a part of the innate cellular...

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PMID: 16475990
DOI: 10.1111/j.1365-2893.2005.00663.x

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