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Article

Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers.

Gastroenterology - 1 Feb 2006

Sato Norihiro, Fukushima Noriyoshi, Chang Rubens, Matsubayashi Hiroyuki, Goggins Michael

Abstract excerpt

BACKGROUND & AIMS: Recently described genome-wide approaches robustly detect many candidate genes that are regulated by DNA methylation, but many of these genes do not represent important targets for functional inactivation. Here we used a microarray-based strategy to identify biologically relevant genes associated with epigenetic silencing in pancreatic cancer. METHODS: We compared information from differential...

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Share to Cell Adhesion Molecules, Neuronal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16472607
DOI: 10.1053/j.gastro.2005.11.008

Genes

RELN
DAB1
VLDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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