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Article

Reduced expression of reelin (RELN) gene is associated with high recurrence rate of hepatocellular carcinoma.

Annals of surgical oncology - 1 Feb 2011

Okamura Yukiyasu, Nomoto Shuji, Kanda Mitsuro, Hayashi Masamichi, Nishikawa Yoko, Fujii Tsutomu, Sugimoto Hiroyuki, Takeda Shin, Nakao Akimasa

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the world's top five causes of cancer-related deaths. Current treatments available ameliorate HCC; however, current therapy fails to completely treat and prevent HCC, as shown by its high recurrence rate. Recently developed genome-wide gene-exp...

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Share to Carcinoma, Hepatocellular
Share to Cell Adhesion Molecules, Neuronal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

Share to Liver Neoplasms

Share to Neoplasm Recurrence, Local

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Source

Identifiers

PMID: 20734148
DOI: 10.1245/s10434-010-1273-z

Genes

RELN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20734148-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Reduced expression of reelin (RELN) gene is associated with high recurrence rate of hepatocellular carcinoma.PMID 20734148Read ↗

Specific mi RNA expression profiles of non‐tumor liver tissue predict a risk for recurrence of hepatocellular carcinomaSemantic proximity Read ↗

Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers.Semantic proximity Read ↗

Epigenetic aberration of the human REELIN gene in psychiatric disorders.Semantic proximity Read ↗

Leukemia inhibitory factor receptor (LIFR) is detected as a novel suppressor gene of hepatocellular carcinoma using double-combination array.Semantic proximity Read ↗

Exploring the mRNA expression level of RELN in peripheral blood of schizophrenia patients before and after antipsychotic treatmentSemantic proximity Read ↗

Integrin α3β1 Represses Reelin Expression in Breast Cancer Cells to Promote InvasionSemantic proximity Read ↗

Transcriptomic profiling reveals an enhancer RNA signature for recurrence prediction in colorectal cancerSemantic proximity Read ↗

Comprehensive analyses of competing endogenous RNA networks reveal potential biomarkers for predicting hepatocellular carcinoma recurrenceSemantic proximity Read ↗

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