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Article

Primary palmar hyperhidrosis locus maps to 14q11.2-q13.

American journal of medical genetics. Part A - 15 Mar 2006

Higashimoto Ikuyo, Yoshiura Koh-ichiro, Hirakawa Naomi, Higashimoto Ken, Soejima Hidenobu, Totoki Tadahide, Mukai Tsunehiro, Niikawa Norio

Abstract excerpt

Primary palmar hyperhidrosis (PPH) is a unique disorder of unknown cause. It is characterized by excessive perspiration of the eccrine sweat gland in the palm, sole, and the axilla. It is presumed that PPH results from overactivation of the cholinergic sympathetic nerve or dysfunction of the autonomic nervous system. There have been no genetic studies on the disease. We performed a linkage analysis of 11 families...

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Identifiers

PMID: 16470694
DOI: 10.1002/ajmg.a.31127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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