Article
Mapping of familial primary pulmonary hypertension locus (PPH1) to chromosome 2q31-q32.
Circulation - 17 Jun 1997
Morse J H, Jones A C, Barst R J, Hodge S E, Wilhelmsen K C, Nygaard T G
Abstract excerpt
BACKGROUND: The pathogenesis of primary pulmonary hypertension (PPH) is unknown, although in some instances families with multiple affected members suggest a genetic etiology. METHODS AND RESULTS: We used microsatellite markers and linkage analysis in a large family with PPH to determine the chromosomal location of their disease gene. We tested a second, ethnically distinct, family for cosegregation of disease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.