Article
Refined localization of a punctate palmoplantar keratoderma gene to a 5.06-cM region at 15q22.2-15q22.31.
The British journal of dermatology - 1 May 2005
Gao M, Yang S, Li M, Yan K L, Jiang Y X, Cui Y, Xiao F L, Shen Y J, Chen J J, Liu J B, Xu S J, Huang W, Zhang X J
Abstract excerpt
BACKGROUND: Punctate palmoplantar keratoderma (PPK) is a rare autosomal dominant cutaneous disorder characterized by numerous hyperkeratotic papules distributed on the palms and soles. Two loci for punctate PPK were recently found to be located on 8q24.13-8q24.21 and 15q22-15q24. However, no genes for this disease have been identified to date. Objectives To refine the previously mapped regions and to identify the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.