Article
A two-stage, genome-wide screen for susceptibility loci in primary Raynaud's phenomenon.
Arthritis and rheumatism - 1 Jul 2000
Susol E, MacGregor A J, Barrett J H, Wilson H, Black C, Welsh K, Silman A, Ollier B, Worthington J
Abstract excerpt
OBJECTIVE: To identify chromosomal regions containing genes involved in the susceptibility to primary Raynaud's phenomenon (RP). METHODS: Six extended families with multiple individuals affected with primary RP (n = 37) were examined for linkage in a 2-stage, whole-genome screen, using a total of 298 microsatellite markers. RESULTS: Multipoint, nonparametric linkage analysis identified 5 areas of possible...
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