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Article

Type A and B RNase P RNAs are interchangeable in vivo despite substantial biophysical differences.

EMBO reports - 1 Apr 2006

Wegscheid Barbara, Condon Ciarán, Hartmann Roland K

Abstract excerpt

We show that structural type A and B bacterial ribonuclease P (RNase P) RNAs can fully replace each other in vivo despite the many reported differences in their biogenesis, biochemical/biophysical properties and enzyme function in vitro. Our findings suggest that many of the reported idiosyncrasies of type A and B enzymes either do not reflect the in vivo situation or are not crucial for RNase P function in vivo,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16470227
DOI: 10.1038/sj.embor.7400641
PMCID: PMC1456918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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