Article

Unlocking efficiency: Native circular RNA surpass linear isoforms in RNase P activity

2025-07-02

Abstract excerpt

RNase P, one of the earliest enzymes identified with RNA as its catalytic component, has been extensively studied across all three domains of life. In this research, we unveil circular isoforms of RNase P RNA within bacterial, fungal, and human cell lines. Comparing the bacterial variant, circM1, with its linear counterpart under diverse conditions revealed its enhanced temperature resistance and superior toleranc...

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Literature Corpus work: d2b5c9ac-1b47-504f-912b-5a88016602ba
DOI: 10.1101/2025.06.30.662392

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