Article
Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.
Gut - 1 Aug 2006
Russell R K, Drummond H E, Nimmo E R, Anderson N H, Noble C L, Wilson D C, Gillett P M, McGrogan P, Hassan K, Weaver L T, Bisset W M, Mahdi G, Satsangi J
Abstract excerpt
BACKGROUND AND AIMS: The OCTN1 (SLC22A4 1672C-->T) and OCTN2 (SLC22A5 -207G-->C) variants within the IBD5 locus have been associated with susceptibility to adult onset Crohn's disease (CD), but their contribution in children has not been examined. METHODS: These OCTN1/2 variants and IBD5 marker single nucleotide polymorphisms (SNPs) (IGR2096a_1, IGR2198a_1, and IGR2230a_1) were examined in 299 Scottish children...
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