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Article

Evidence for association of OCTN genes and IBD5 with ulcerative colitis.

Gut - 1 Jun 2006

Waller S, Tremelling M, Bredin F, Godfrey L, Howson J, Parkes M

Abstract excerpt

BACKGROUND AND AIMS: Genetic association between Crohn's disease (CD) and OCTN1 (SLC22A4) C1672T/OCTN2 (SLC22A5) G-207C variants in IBD5 has recently been reported. These genes encode solute carriers and the association was suggested to be distinct from the background IBD5 risk haplotype. There have been conflicting reports of the association between markers in the IBD5 region and ulcerative colitis (UC) and...

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Topics

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Share to Chromosomes, Human, Pair 5
Share to Colitis, Ulcerative
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammatory Bowel Diseases

Share to Nod2 Signaling Adaptor Protein

Share to Organic Cation Transport Proteins

Share to Solute Carrier Family 22 Member 5

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Source

Open in PubMed Open full text

Identifiers

PMID: 16361305
DOI: 10.1136/gut.2005.084574
PMCID: PMC1856215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for association of OCTN genes and IBD5 with ulcerative colitis.PMID 16361305Read ↗

The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease.Semantic proximity Read ↗

Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease.Semantic proximity Read ↗

Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.Semantic proximity Read ↗

Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.Semantic proximity Read ↗

Role of CARD15, DLG5 and OCTN genes polymorphisms in children with inflammatory bowel diseases.Semantic proximity Read ↗

Contribution of the IBD5 locus to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

OCTNs: will the real IBD5 gene please stand up?Semantic proximity Read ↗

Functional variants of OCTN cation transporter genes are associated with Crohn disease.Semantic proximity Read ↗

Polymorphisms in the IBD5 locus are associated with Crohn disease in pediatric Ashkenazi Jewish patients.Semantic proximity Read ↗

Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.Semantic proximity Read ↗

Advances in the genetics of inflammatory bowel disease.Semantic proximity Read ↗

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