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Article

Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.

European journal of human genetics : EJHG - 1 Feb 2006

Martínez Alfonso, Martín Maria Del Carmen, Mendoza Juan L, Taxonera Carlos, Díaz-Rubio Manuel, de la Concha Emilio G, Urcelay Elena

Abstract excerpt

The SLC22A4 and SLC22A5 genes within the IBD5 risk locus encode the organic cation transporters OCTN1 and OCTN2. Two variants, 1672C>T in SLC22A4 and -207G>C in SLC22A5, were shown to alter these genes' functions and were identified as genetic susceptibility factors for Crohn's disease (CD). We p...

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Identifiers

PMID: 16333318
DOI: 10.1038/sj.ejhg.5201529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16333318-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.PMID 16333318Read ↗

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