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Article

OCTNs: will the real IBD5 gene please stand up?

World journal of gastroenterology - 21 Jun 2006

Silverberg Mark-S

Abstract excerpt

Crohn's disease and ulcerative colitis are inflammatory disorders of the gastrointestinal tract with a substantial heritable component. The IBD5 region on chromosome 5q31 is one of only two loci widely confirmed to be associated with Crohn's disease in multiple independent cohorts. Although many populations have demonstrated association with IBD5, there remains uncertainty as to the causal variant within the...

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Share to Polymorphism, Genetic
Share to Organic Cation Transport Proteins
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16773684
DOI: 10.3748/wjg.v12.i23.3678
PMCID: PMC4087460

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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OCTNs: will the real IBD5 gene please stand up?PMID 16773684Read ↗

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Evidence for association of OCTN genes and IBD5 with ulcerative colitis.Semantic proximity Read ↗

Contribution of the IBD5 locus to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Role of the IBD5 susceptibility locus in the inflammatory bowel diseases.Semantic proximity Read ↗

Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease.Semantic proximity Read ↗

Crohn's disease and genetic hitchhiking at IBD5.Semantic proximity Read ↗

Sequence variation, linkage disequilibrium and association with Crohn's disease on chromosome 5q31.Semantic proximity Read ↗

IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis.Semantic proximity Read ↗

Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.Semantic proximity Read ↗

Functional variants of OCTN cation transporter genes are associated with Crohn disease.Semantic proximity Read ↗

Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease.Semantic proximity Read ↗

IBD5: the second Crohn's disease gene?Semantic proximity Read ↗

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