Article
Contribution of the IBD5 locus to Crohn's disease in the Swedish population.
Scandinavian journal of gastroenterology - 1 Feb 2007
Törkvist Leif, Noble Colin L, Lördal Mikael, Sjöqvist Urban, Lindforss Ulrik, Nimmo Elaine R, Löfberg Robert, Russell Richard K, Satsangi Jack
Abstract excerpt
OBJECTIVE: Recent data have controversially suggested that variants of the organic cation transport genes SLC22A4 (OCTN1) and SLC22A5 (OCTN2) are responsible for the contribution of IBD5 to disease susceptibility in Crohn's disease (CD). The objective of this study was to assess the contribution of the SLC22A4 variant (1672T) and SLC22A5 variant (-207C) together with three IBD5 haplotype markers in the previously...
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