Article
Morphological characterization of the retinal degeneration in three strains of mice carrying the rd-3 mutation.
Visual neuroscience - 1 Jan 2000
Linberg Kenneth A, Fariss Robert N, Heckenlively John R, Farber Debora B, Fisher Steven K
Abstract excerpt
Retinal development in 3 strains of rd-3/rd-3 mutant mice, previously shown to have different rates of degeneration, was studied using light, electron, and immunofluorescence microscopy. The time course and phenotype of the degeneration as well as details on the mechanism of massive photoreceptor cell loss are compared with other known retinal degenerations in mice. Up until postnatal day (P) 10, the retinas of...
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