Article
Inner retina remodeling in a mouse model of stargardt-like macular dystrophy (STGD3).
Investigative ophthalmology & visual science - 1 Apr 2010
Kuny Sharee, Gaillard Frédéric, Mema Silvina C, Freund Paul R, Zhang Kang, Macdonald Ian M, Sparrow Janet R, Sauvé Yves
Abstract excerpt
Purpose. To investigate the impact of progressive age-related photoreceptor degeneration on retinal integrity in Stargardt-like macular dystrophy (STGD3). Methods. The structural design of the inner retina of the ELOVL4 transgenic mouse model of STGD3 was compared with that of age-matched littermate wild-type (WT) mice from 1 to 24 months of age by using immunohistofluorescence and confocal microscopy and by...
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