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Article

Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).

Molecular vision - 28 Feb 2005

Pang Ji-Jing, Chang Bo, Hawes Norman L, Hurd Ronald E, Davisson Muriel T, Li Jie, Noorwez Syed M, Malhotra Ritu, McDowell J Hugh, Kaushal Shalesh, Hauswirth William W, Nusinowitz Steven, Thompson Debra A, Heckenlively John R

Abstract excerpt

PURPOSE: To report the phenotype and characterization of a new, naturally occurring mouse model of hereditary retinal degeneration (rd12). METHODS: The retinal phenotype of rd12 mice were studied using serial indirect ophthalmoscopy, fundus photography, electroretinography (ERG), genetic analysis including linkage studies and gene identification, immunohistochemistry, and biochemical analysis. RESULTS: Mice...

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Source

Identifiers

PMID: 15765048

Genes

RPE
RPE65
ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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