Article
New mouse primary retinal degeneration (rd-3).
Genomics - 1 Apr 1993
Chang B, Heckenlively J R, Hawes N L, Roderick T H
Abstract excerpt
A new mouse retinal degeneration that appears to be an excellent candidate for modeling human retinitis pigmentosa is reported. In this degeneration, called rd-3, differentiation proceeds postnatally through 2 weeks, and photoreceptor degeneration starts by 3 weeks. The rod photoreceptor loss is essentially complete by 5 weeks, whereas remnant cone cells are seen through 7 weeks. This is the only mouse homozygous...
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