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Article

Actin-depolymerizing factor, ADF/cofilin, is essentially required in assembly of Leishmania flagellum.

Molecular microbiology - 1 Nov 2008

Tammana T V Satish, Sahasrabuddhe Amogh A, Mitra Kalyan, Bajpai Virendra K, Gupta Chhitar M

Abstract excerpt

ADF/cofilins are ubiquitous actin dynamics-regulating proteins that have been mainly implicated in actin-based cell motility. Trypanosomatids, e.g. Leishmania and Trypanosoma, which mediate their motility through flagellum, also contain a putative ADF/cofilin homologue, but its role in flagellar motility remains largely unexplored. We have investigated the role of this protein in assembly and motility of the...

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Identifiers

PMID: 18793337
DOI: 10.1111/j.1365-2958.2008.06448.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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