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Article

A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97.

Biochemical and biophysical research communications - 31 Mar 2006

Mathur Rajesh, Choi Woo-Sung, Eldstrom Jodene, Wang Zhuren, Kim Jason, Steele David F, Fedida David

Abstract excerpt

We have previously reported that SAP97 enhancement of hKv1.5 currents requires an intact Kv1.5 N-terminus and is independent of the PDZ-binding motif at the C-terminus of the channel [J. Eldstrom, W.S. Choi, D.F. Steele, D. Fedida, SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism, FEBS Lett. 547 (2003) 205-211]. Here, we report that an interaction between the two proteins can be detected...

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Identifiers

PMID: 16466689
DOI: 10.1016/j.bbrc.2006.01.110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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