Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C-->T mutation.

Neurobiology of aging - 1 Mar 2006

Durga Jane, Anteunis Lucien J C, Schouten Evert G, Bots Michiel L, Kok Frans J, Verhoef Petra

Abstract excerpt

Vascular disease and its risk factors have been associated with the age-related hearing loss. We examined the association of elevated plasma homocysteine and its determinants with hearing levels. Pure-tone air conduction thresholds in 728 individuals with sensorineural hearing loss were not associated with homocysteine, erythrocyte folate and Vitamin B6. Low concentrations of serum folate and Vitamin B12 were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Auditory Threshold
Share to Folic Acid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hearing Loss, Sensorineural

Share to Homocysteine

Share to Incidence

Share to Netherlands

Share to Severity of Illness Index

Share to Vitamin B 12

Source

Identifiers

PMID: 16464657
DOI: 10.1016/j.neurobiolaging.2005.03.002

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C-->T mutation.PMID 16464657Read ↗

Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study.Semantic proximity Read ↗

Association between polymorphisms in genes encoding methylenetetrahydrofolate reductase and the risk of Ménière's disease.Semantic proximity Read ↗

Polymorphisms in folate metabolism genes are associated with susceptibility to presbycusis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T gene mutation as risk factor for sudden sensorineural hearing loss: association with plasma homocysteine, folate and cholesterol concentrations.Semantic proximity Read ↗

Impact of methionine synthase gene and methylenetetrahydrofolate reductase gene polymorphisms on the risk of sudden sensorineural hearing loss.Semantic proximity Read ↗

MTHFR 677T is a strong determinant of the degree of hearing loss among Polish males with postlingual sensorineural hearing impairment.Semantic proximity Read ↗

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing LossSemantic proximity Read ↗

Methylenetetrahydrofolate reductase gene mutations as risk factors for sudden hearing loss.Semantic proximity Read ↗

Low blood folates in NTD pregnancies are only partly explained by thermolabile 5,10-methylenetetrahydrofolate reductase: low folate status alone may be the critical factor.Semantic proximity Read ↗

Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele.Semantic proximity Read ↗

The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability.Semantic proximity Read ↗

Homocysteine, B vitamins, methylenetetrahydrofolate reductase gene, and risk of primary open-angle glaucoma: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.